Mexican authorities say they have arrested two people in connection with an explosive attack on a police patrol that killed six people and wounded 15 last Tuesday in a region hard hit by drug cartel-related violence.

Joaquin Mendez, the prosecutor of Jalisco state, told journalists the two will be charged with murder, causing injury, and attacks against representatives of authority.

The state of Jalisco has the most missing people among the country's 32 states since 1962.

The two were arrested in an operation involving municipal authorities and the military.

The attack with seven homemade bombs on Tuesday July 11 targeted police and staff from the state prosecutor's office in Tlajomulco de Zuniga, a suburb of the city of Guadalajara.

Four police members and two civilians were killed and 15 others were injured.

Mexico has recorded more than 350,000 murders since the launch of a controversial military anti-drug offensive in 2006, most attributed to criminal organizations.